We study how the neuroendocrine system orchestrates postembryonic development, and how hormones of the thyroid and adrenal glands influence development of the central nervous system and pituitary gland.

Our molecular and cellular studies are integrated with organismic level questions of physiological adaptation to environmental change and the evolution of vertebrate neuroendocrine systems.

Metamorphosis of Xenopus laevis
electro TON 1
Cells expressing enhanced green fluorescent protein in the anterior preoptic area of Xenopus tadpole brain.
Tadpoles were transfected by electroporation-mediated gene transfer.

Photo credits: Xenopus developmental stages: David Bay

The research described on this web site was conducted with funding from the National Science Foundation of the United States of America, The National Institutes of Health, The American Thyroid Association, and the Office of the Vice President for Research, the College of Literature, Science and the Arts, the Rackham Graduate School and the Pheonix Project of the University of Michigan, and the Great Lakes Protection Fund of the Michigan Department of Environmental Quality.